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This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group;
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Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable;
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-of-the-art. It identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new;
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emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments
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after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly;
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in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and;
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Alexander Fleming's discovery of penicillin in his London lab in 1928 led to its eventual development by a team at Oxford University;
Vergelijkbare producten zoals The Mould In Dr Florey's Coat
of bacteria to mutate and develop drug resistance. Yet the development of new antibiotics has not kept up with bacterial evolution, especially since;
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Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their;
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and Development, in conjunction with British counterparts, assumed control; penicillin became a top-secret matter of national security, second;
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Perhaps the greatest single advance in the history of medical thought, the discovery of the germ led directly to safe surgery, large-scale;
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Antibiotics: Challenges, Mechanisms, Opportunities details the contemporary challenges for discovery, optimization, and advancement of new;
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also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery;
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investigative information for health-related applications. In addition, the book addresses the design and development of antibiotics with advanced;
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strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic;
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function and pathway discovery in bacteria, Adding a diazo-transfer reagent to culture to generate secondary metabolite probes for click chemistry;
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Understanding antibiotic chemotherapy at the ecological level is necessary for more permanent advances in development and in the usage;
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Understanding antibiotic chemotherapy at the ecological level is necessary for more permanent advances in development and in the usage;
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The discovery of antibiotics in the early 20th century fundamentally transformed human and veterinary medicine. Antibiotics now save;
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This book describes the most important advances in modern medicine. It starts with the introduction of the first antibiotic to the present;
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system; however, selective pressure among bacteria allows the development for antibiotic resistance. Foodborne Pathogens and Antibiotic;
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Ambler class-B metallo- -lactamases. The closing study will walk readers through the discovery and golden age of -lactam, its mechanism;
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. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus;
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, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the;
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continuing impact of his work. * Provides a full description of the methods used in the first systematic search and discovery of an antibiotic;
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This volume describes important medical discoveries, from the introduction of the first antibiotic to the present, where serendipity;
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