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This book provides a comprehensive introduction to statistical methods for designing early phase dose-finding clinical trials. It will;
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This book deals with advanced methods for adaptive phase I dose-finding clinical trials for combination of two agents and molecularly;
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for more established researchers from which to build A collection of material for an advanced course in early phase clinical trials;
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-finding in phase I/II clinical trials and presents practical guidance on their correct use. * Includes an introductory section, summarizing the;
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As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to;
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properties, and operating characteristics for phase I, II, and III clinical trials as well as an introduction to phase IV trials. Many practical;
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is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I-II;
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is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I-II;
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. An Introduction to Statistics in Early Phase Trialsdescribes the practical design and analysis of these importantearly phase clinical trials;
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In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to;
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In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to;
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phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an;
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phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an;
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Statistical Approaches in Oncology Clinical Development : Current Paradigm and Methodological Advancement presents an overview;
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Get the tools you need to use SASĀ® in clinical trial design! Unique and multifaceted, Modern Approaches to Clinical Trials Using SAS;
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Get the tools you need to use SAS in clinical trial design! Unique and multifaceted, Modern Approaches to Clinical Trials Using SAS;
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developments involved in the design and analysis of cancer clinical trials, incorporating updates to all four parts: Phase I trials;
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developments involved in the design and analysis of cancer clinical trials, incorporating updates to all four parts: Phase I trials;
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-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design;
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-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design;
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Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology explores statistics used in day-to-day clinical;
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present Bayesian tools useful in early (Phase I) and middle (Phase II) clinical trials as well as two recent Bayesian adaptive Phase II studies;
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This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied;
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This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied;
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, researchers, and practitioners * An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human;
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begins with a broad introduction from a regulatory perspective to different types of multiplicity problems that commonly arise in confirmatory;
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how biostatistics in clinical trials is an integration of many fundamental scientific principles and statistical methods. Teach Your;
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