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Transporters as Drug Carriers: Structure, Function, Substrates

transport across those physiological barriers relevant for drug uptake, distribution and excretion. As a result, this key resource lays the;

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Membrane Transporters as Drug Targets

structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for;

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Transporters in Drug Development

and biomarkers are suggested for studies of the transporters' impact on the pharmacokinetics of drug substrates/candidates interacting on;

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Channels, Carriers, and Pumps

movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well;

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A Structure-Function Toolbox for Membrane Transporter and Channels

A Structure-Function Toolbox for Membrane Transporter and Channels, Volume 594, a new release in the Methods in Enzymology series;

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Drug Metabolism and Pharmacokinetics Quick Guide

, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and;

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Drug Transporters: Molecular Characterization and Role in Drug Disposition

for studying drug transporters. Contributions by an international panel of leading researchers address advances in transporters as drug;

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Drug-Drug Interactions

Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical;

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Pharmacogenomics Of Human Drug Transporters

Transporters reviews individual drug transporters, including specific transporter families and clinical implications. This book serves as a;

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Dopamine Transporters

in diseases such as Parkinson's, schizophrenia, attention deficit hyperactivity disorder (ADHD), Tourette syndrome, and drug abuse (in particular;

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Transporters as Drug Targets

explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including;

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Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all;

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Neuronal Chloride Transporters in Health and Disease

-independent functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational;

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Ocular Transporters and Receptors

emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to;

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The Transporter Factsbook

/>The Academic Press FactsBook Series has established itself as the best source of easily-accessible and accurate facts about protein groups;

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Basic Epithelial Ion Transport Principles and Function

, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid;

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Pumps, Channels And Transporters

Describes experimental methods for investigating the function of pumps, channels and transporters * Covers new emerging analytical methods;

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Drug Transporters

A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the bodyThe;

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SH Domains

of the morphology assembly of fibrils, and mechanotransduction makes these molecules attractive drug targets. Substrates, inhibitors and;

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Transporters in Drug Discovery and Development

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide;

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Handbook on Supercritical Fluids

in small structures and poorly wettable substrates. Deposition and array formation of metal and metal sulphide nanoparticles on various substrates;

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ABC Transporters and Multidrug Resistance

This book gathers present knowledge on the involvement of ABC transporters in drug transport and resistance. Bringing together updated;

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Membrane Transporters in Drug Discovery and Development

Studies of membrane transporters have had a great impact on our understanding of human diseases and the design of effective drugs;

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Interactions between membrane transporters and phospholipids

multidrug transporter LmrP are also discussed. Using this membrane protein as a model, we demonstrated that the protein structure and function;

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Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters

the role of drug metabolism enzymes, transporters in disposition and drug-drug interactions, as well as strategies for evaluating drug;

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Structure and Function of Intrinsically Disordered Proteins

structure-function paradigm to herald new breakthroughs in drug development. Structure and Function of Intrinsically Disordered Proteins thoroughly;

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Cancer Drug Resistance

and Methods contains chapters that cover topics such as: studying the mechanics of resistance to DNA damaging therapeutic drugs; studies to;

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