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Therapeutic Oligonucleotides

The potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools are;

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Therapeutic Oligonucleotides

The field of oligonucleotide therapeutics research is ripe with the prospect of new discoveries. In Therapeutic Oligonucleotides: Methods;

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Handbook of Analysis of Oligonucleotides and Related Products

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic;

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Handbook of Analysis of Oligonucleotides and Related Products

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic;

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Nucleic Acids Chemistry

, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers;

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Oligonucleotide-Based Therapies

of oligonucleotide (ON) therapeutics. Covering topics from the study of antisense and anti-gene effects to oligonucleotides in the context of drug discovery;

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A Comprehensive Guide to Aptamers

therapeutic oligonucleotides. Additionally, key examples of targeted delivery of the most common nucleic acid therapeutics, including small;

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Pharmaceutical Biotechnology: Fundamentals and Applications, Third Edition

, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including;

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Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning

When first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level;

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Oligonucleotide Array Sequence Analysis

Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. Automated synthesisers allow the;

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Applied Antisense Oligonucleotide Technology

of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms;

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Molecular and Cellular Methods in Developmental Toxicology

important new trends, such as evaluation of the safety of therapeutic antisense oligonucleotides, studies of the role of cell death in abnormal;

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Neuromuscular Disorders

in clinical neuromuscular care, and a team of world-renowned contributors coverall management and therapeutic considerationsregarding thefull range;

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The Aptamer Handbook

of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers;

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Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides

Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the;

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Antisense-Based Drugs and Therapeutics

clinical experience with antisense oligonucleotides. Examines principles and tools for scientists in both pre-clinical and clinical settings and;

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Polysaccharide based Nano-Biocarrier in Drug Delivery

delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment;

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Polysaccharide based Nano-Biocarrier in Drug Delivery

delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment;

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Advances in Nucleic Acid Therapeutics

provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield;

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Pharmacokinetics and Pharmacodynamics of Biotech Drugs

, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges;

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NMR Spectroscopy Techniques

experiments, and contains material on: three- and four-dimensional NMR; the NMR analysis of peptides, proteins, carbohydrates and oligonucleotides;

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Advances in Chromatography

latest techniques in the use of capillary electrophoresis and mass spectrometry for sequencing antisense oligonucleotides, and more.;

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Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors

in which gene-based interventions are presently plausible, and presents case studies of current research using both synthetic oligonucleotides and;

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Micro- and Nanosystems for Biotechnology

will address the novel application of micro and nanosystems in biological research, diagnostics and therapeutics. Speci?cally the book will;

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Liposomes, Part D

in EnzymologyLiposome volumes A, B, and C. Covers antibody or ligand targeted liposomes; environment sensitive liposomes; liposomal oligonucleotides;

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Biophysics of DNA-Antibiotic Complexes

interactions of heterocyclic anti-tumour antibiotics (Actinomycins, as typical example) with DNA, poly-nucleotides, oligonucleotides, and aggregates;

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PEGylated Protein Drugs

describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.;

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