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damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer;
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senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and;
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Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985;
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pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient;
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pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient;
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diagnosis and prognosis of cancer because its expression strongly correlates with the potential tumour progression. Ninety percent of human cancers;
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information regarding telomere dynamics in response to stress or stimuli. Telomeres and Telomerase: Methods and Protocols, Second Edition builds upon;
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stages of telomere research, telomerase, heralded as a potential cure for cancer and diseases related to aging, attracted the voracious interest;
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of telomeres, capable to surprise the cells. Telomeres provide an introduction to the history of our cells which govern the quality of life and status;
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This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume;
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The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This;
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This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging;
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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects;
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in the Aging Patient. Articles in this issue include: The Effects of Aging on Lung Structure and Function; Immunosenescence and the Lungs;
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biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate;
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resistance and sensitivity; lifespan, aging and cancer; regulation and dysregulation of metabolism; signaling and gene regulation; environment and;
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A high proportion of cancer occurs primarily in older persons, and incidence of the major cancers is greater. This, combined with the;
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Science is on the cusp of a revolutionary breakthrough. We now understand more about ageing - and how to prevent and reverse it - than ever;
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As the lifespan of humans increases, research into aging and its related pathological conditions is gaining momentum. This book is the;
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sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals;
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informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty, cancer, and dementia. Dr;
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striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders;
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disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency;
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in the blight fungus ustilago maydis; roles of mirnas in cancers; and genetic programming for music.;
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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular;
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