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techniques for identifying and synthetically designing novel drugs.;
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characterized by unique features that make them promising targets for structure-based drug design. Lastly, the book proposes a mathematical model;
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of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design;
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A guide to applying the power of modern simulation tools to better drug design Biomolecular Simulations in Structure-based Drug Discovery;
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subject of structure and ligand-based drug design, and it provides the most up-to-date information on a wide range of topics for the practising;
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molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity;
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Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use;
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, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease;
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-based strategies. Different chem-bioinformatic modeling strategies that can be applied for design of multi-target drugs as well as important;
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. The word malaria comes from the Italian mal'aria for bad airs . Malaria is transmitted to humans via the bite of the infected female;
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products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state;
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chemogenomics and polypharmacology, and fragment-based drug design Illustrates advances in biomolecular targeting using case studies and emerging;
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drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize;
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Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development;
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, such as structure-based drug designing, quantitative structure activity relationship, pharmacophore modelling, and docking studies for;
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, leishmaniasis and malaria. Finally, the roles of polyamine analogues in chemoprevention, polyamine-containing vectors for gene delivery, and the design;
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This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists;
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utilized by industry and academia for ligand design. Featuring contributions from more than fifty pre-eminent scientists, Computational Medicinal;
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methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the;
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and practice of structure-based drug discovery not only illustrates leading-edge science but also provides the scientific background for the;
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, Quantitative Drug Design: A Critical Introduction, Second Edition shows scientists how to apply QSAR techniques at a state-of-the-art level. New;
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, Quantitative Drug Design: A Critical Introduction, Second Edition shows scientists how to apply QSAR techniques at a state-of-the-art level. New;
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become an integral part of ongoing drug discovery research. In Chemical Library Design, experts in the field provide methods and detailed;
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in therapeutics and indicating future directions, Receptor-Based Drug Design introduces novel computer-assisted strategies for the design of new;
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in therapeutics and indicating future directions, Receptor-Based Drug Design introduces novel computer-assisted strategies for the design of new;
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This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target;
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