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of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk;
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Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials;
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This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Elin R. Sigurdson, is devoted to Clinical Trials in Surgical;
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, number of events, and independence or noninformativeness of the censoring mechanisms relative to the event. Design and Analysis of Clinical;
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, Noninferiority Testing in Clinical Trials: Issues and Challenges explains how to choose the NI margin as a small fraction of the therapeutic effect;
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Testing in Clinical Trials: Issues and Challenges explains how to choose the NI margin as a small fraction of the therapeutic effect of the active;
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Uses a relatively small number of key principles, in conjunction with a modest repertoire of statistical techniques to help the reader;
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Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the;
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Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the;
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to little sensitivity due to small samples, as well as inappropriate hypotheses based on biased prior trials. Additional flaws were being;
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diseases and small biomarker defined subsets in oncology, where the required sample sizes for traditional clinical trial designs may not be;
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This extensively revised second edition is a unique and portable handbook focusing on clinical trials in surgery. It includes new;
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Clinical Trials Explained has been designed in consultation with doctors and patients who have taken part in trials, providing an essential;
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The second edition of Oncology Clinical Trials has been thoroughly revised and updated and now contains the latest designs and methods;
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This set includes Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs & Methods;
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A systematic approach to all aspects of designing and conducting clinical trials The success or failure of clinical trials hinges on;
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Design and Analysis of Clinical Trials for Predictive Medicine provides statistical guidance on conducting clinical trials for predictive;
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the success probability of an experiment Success Probability Estimation with Applications to Clinical Trials details the use of success;
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Clinical Trials in Older Adults is the first book to consider the methodological issues underlying the evaluation of new treatments;
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A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource;
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Global Clinical Trials for Alzheimer's Disease is a handy one-stop reference for researchers and physicians planning and conducting;
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to low sensitivity due to small samples, as well as inappropriate hypotheses based on biased prior trials. Additional flaws were recognized;
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There is growing recognition that the United States' clinical trials enterprise (CTE) faces great challenges. There is a gap between what;
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A comprehensive volume on clinical trials that covers all important disease and therapeutic areas together with methodologies, phase I/II;
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Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule;
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Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule;
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This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials;
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