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Polypharmacology in Drug Discovery

Polypharmacology can be the two-faced Janus in drug discovery and pharmacology: an adverse, off-target safety risk in some cases or a;

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Polypharmacology

polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology that is needed. This;

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Approaching Complex Diseases

. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug;

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The Practice of Medicinal Chemistry

screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book;

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Structural Biology in Drug Discovery: Methods, Techniques, and Practices

chemogenomics and polypharmacology, and fragment-based drug design Illustrates advances in biomolecular targeting using case studies and emerging;

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Data Mining in Drug Discovery

polypharmacology, where data mining can substantially enhance the research effort. The final section of the book is devoted to systems biology approaches;

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Systems Chemical Biology

panels and web-based tools for polypharmacology prediction. Written in the highly successful Methods in Molecular Biology series format, chapters;

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Taxaceae and Cephalotaxaceae

level upward Details the polypharmacology of these plants and associated microbe compounds in relation to pharmaceutical design and;

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Molecular Diagnostics and Treatment of Pancreatic Cancer

comprehension across conventional length and temporal scalesCoverage includes novel applications in targeted drugs, polypharmacology, network;

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