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Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials;
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testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, transgenic models, and gene;
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screening drugs against pancreatic cancer, X-ray sensitizer screen, patient derived tumor model for esophageal cancer, renal cancer and metastasis;
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inducible systems, as well as models derived using transposon-based insertional mutagenesis, RNA interference, viral-mediated gene delivery, and;
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uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists;
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models of lower-grade gliomas, medulloblastoma, and brain metastases; ex vivo methods for glioblastoma patient-derived cell lines and organotypic;
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design, characterization, in vitro cellular uptake, cytotoxicity, to in vivo pharmacokinetics, biodistribution, and xenograft tumor model of the;
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of dormancy have been identified, and the relevance of these models to human cancer patients is recognized. Data derived from studies of organ;
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on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer;
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the various available therapeutic modalities into a coherent care program for the solid tumor patient. As a central theme, the chapters;
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the various available therapeutic modalities into a coherent care program for the solid tumor patient. As a central theme, the chapters;
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cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research;
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Measurement of solid tumor response to treatment relies mainly on imaging. WHO tumor response criteria and, more recently, RECIST (response;
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Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components;
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Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components;
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New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but;
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, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing;
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of cancer-derived enzyme products. Specific chapters cover Circulating peptidome and tumor-resident proteolysis, Colon tumor secretopeptidome;
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lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived;
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Tumors often start out as a benign growth, but gradually progress toward the malignant stage over a relatively long period of time. Tumor;
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in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumors, otherwise known as markers or indicators. It;
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When successful neurosurgeon John MacAndrews performs a routine operation to remove a tumor, the patient undergoes a severe personality;
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Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors;
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approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived;
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This volume is based on the Workshop on Systems Biology of Tumor Dormancy meeting, held July 25th to July 28th, 2011. The first annual CCSB;
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microenvironment, including endogenous and exogenous DC, multiple DC populations, molecular pathways responsible for DC dysfunction, tumor-derived factors;
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Recent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological;
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