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This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating;
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This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating;
Vergelijkbare producten zoals One Step Generation of a Drug Releasing Microarray for High Throughput Small Vol
move away from microarray-based technology to ultra high-throughput, massively parallel genomic sequencing (Next Generation Sequencing, NGS;
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High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug;
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are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for;
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High-throughput RNAi screening remains one of the most widely used technologies to perform target identification and validation studies;
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covered is high-content, 3D cell-based imaging assays of tissue functions on miniaturized tissue constructs for high-throughput, predictive;
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Due to their novel concepts and extraordinary high-throughput sequencing capacity, the next generation sequencing methods allow;
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Due to their novel concepts and extraordinary high-throughput sequencing capacity, the next generation sequencing methods allow;
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screening of chemical hits, rational lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based;
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, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. Unique for its treatment of platform;
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the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug;
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illustrates how SPE techniques significantly contribute to the preparation of samples for a wide variety of analytical techniques. It provides step-by;
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Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply;
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High Throughput Screening (HTS) is one of several hit identification approaches that are part of a developing and evolving toolbox for the;
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provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs;
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The advances in genomic technologies, such as microarrays and high throughput sequencing,have expanded the realm of possibilities for;
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In most modern biomedical research projects, application of high-throughput genomic, proteomic, and transcriptomic experiments has;
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does not completely eliminate the need for experiments, lab-on-chip type of approaches coupled with computational high throughput screening;
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the power and limitations of label-free in all areas of drug discovery. Label-free technologies discussed include SPR, NMR, high-throughput;
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is written for statisticians who are interested in modeling and analyzing high-throughput data. Chapters by experts in the field offer a thorough;
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in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for;
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for DNA and protein chips, as well as spotters and scanners. The book also covers high throughput screening, patent research, and the minimum;
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Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can;
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miniaturized high throughput technique, DNA microarrays, tailored for studying genome-scale genotyping and gene-expression profiling. An overview;
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New strategies and techniques for today's fast-paced discovery process Today, the pressure is on for high-throughput approaches to;
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into one how to manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method;
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