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excitability, models of epileptic disorders, targets for anti-epileptic drugs and rational approaches to therapy. Each chapter provides a review of a;
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This book presents current research in the study of the prevention, recognition and treatment of seizures and the use of anti-epileptic;
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This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models;
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of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular;
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and molecular perspective, with particular attention to the mechanisms of drug action the fundamental basis for proper clinical use- without;
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This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti;
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research works of various renowned international experts from distinct educational backgrounds. This book deals with basic molecular and cellular;
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conditions, as well as an overview of studies focusing on molecular chaperones as potential targets for designing novel anti-parasitic drugs, are;
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of epilepsies. Chapters cover treatments with anti-epileptic drugs, neurosurgical interventions and other pharmacological and non-pharmacological;
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Leading investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole;
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. In the field of cellular biology, toxins have become invaluable as tools for the manipulation and investigation of fundamental cellular and;
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Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal;
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This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging;
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Viruses interact with host cells in ways that uniquely reveal a great deal about general aspects of molecular and cellular structure and;
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Institute of Physiology, Tbilisi, Georgia) and is devoted to the experimental investigation of systemic, cellular and molecular mechanisms;
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tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand;
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tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand;
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For some years, international guidelines on the management of asthma have stressed the importance of early intervention with anti;
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in disease states and their potential use as molecular targets for novel therapeutic agents.;
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. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory;
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This work concentrates on cellular and molecular toxicity of selected well-known drugs or chemicals on the cardiovascular system. The;
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Lipids are responsible not just for constituting cellular membrane but also for storing energy, transducing signaling, and modifying;
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associated cellular and molecular biomarkers of carcinogenesis. The pharmacologic and/or mechanistic classes discussed range from antimutagens;
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advice. This pocket-sized, user-friendly guide will be a valuable resource for all those involved in the care of patients with epileptic seizures.;
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comparative modeling, molecular docking, and dynamics simulations of novel drug targets and in silico validation and ADMET analysis for best lead;
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internationally renowned experts. Part 1 describes the basic mechanisms. Tumor-angiogenic signaling pathways are presented as new potential targets for;
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