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Modifications of Nuclear DNA and its Regulatory Proteins

DNA methylation is essential for the normal development and functioning of organisms. This volume discusses the latest developments;

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Epigenetics, Nuclear Organization & Gene Function

principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that;

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Epigenetics, Nuclear Organization & Gene Function

principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that;

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Epigenomics

, the accessibility of DNA to gene regulatory components and the ability of chromatin to interact within nuclear complexes. While a;

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Sperm Nuclear Maturation

condensation'. This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa.;

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Chromosomal Nonhistone Protein: Volume III

The third volume of the Chromosomal Nonhistone Proteins treatise deals with the isolation and analysis of chromosomal proteins in general;

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Molecular Determinants of Radiation Response

and proteins result in substantive modifications of cellular response to DNA injury. Given the importance of therapies that induce DNA injury;

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Nucleic Acids Chemistry

, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.;

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Mechanisms of Genome Protection and Repair

in the area of protective and regulatory mechanisms associated with DNA damage. The mechanisms ruling the recognition of damaged nucleotides;

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Lysine-based Post-translational Modification of Proteins

processes, including metabolism, innate immunity, cell motility, DNA-damage repair and mitochondrial function, all of which are discussed in this;

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Progress in DNA Damage Research

to carry out its function and appreciably increase the likelihood of tumour formation. The vast majority of DNA damage affects the primary;

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Single-Stranded DNA Binding Proteins

, recombination, and repair machinery access to genomic information. However, DNA unwinding comes with inherent risks to genome stability. To help;

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New Research on DNA Damage

DNA damage, due to environmental factors and normal metabolic processes inside the cell, occurs at a rate of 1,000 to 1,000,000 molecular;

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Mitochondrial Diseases

structure and its various mutations. It further describes some key nuclear-encoded proteins involved in energy transduction and presents new aspects;

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DNA Modification Detection Methods

Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications;

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Histones

Histones are DNA-binding proteins that help in the packaging of DNA to fit into the cell nucleus in a hierarchy of organisation. During the;

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SIRT6 Activities in DNA Damage Repair and Premature Aging

regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and can have significant;

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Regulatory Mechanisms in Transcriptional Signaling

Regulatory Mechanisms in Transcriptional Signaling, volume of Progress in Molecular Biology and Translational Science, includes in-depth;

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The Histone Code and Beyond

of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural;

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Chromatin Dynamics in Cellular Function

in DNA replication and repair, and current models of nucleosome-remodeling mechanisms.;

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Dna Recombination

process directs the repair of many DNA lesions in somatic cells and generates genetic variation in sperm and egg cells during meiosis. It is a;

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Systems Biology of RNA Binding Proteins

, functional and spatial dynamics of the target RNA define a putative mRNP code . These cis-regulatory RNA elements can be found in the 5' and 3;

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The Histone Code and Beyond

of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural;

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Microwave Effects on DNA and Proteins

For several years, researchers have been reporting the effects of microwave radiation/heating on both the structure and function of DNA;

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Mitochondrial Oxidative Phosphorylation

subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a;

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Bioanalytics

determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids such as DNA and RNA;

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Einde inhoud

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