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Mechanisms of Cell Death and Opportunities for Therapeutic Development, volume four in the Perspectives in Translational Cell Biology;
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In multicellular organisms, cell death is required for normal development, homeostasis, and the elimination of infected or injured cells;
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. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental;
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cancer is presented as a central paradigm for the consequences of derangements in the interplay between cell survival and cell death. At the same;
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diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts;
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International experts evaluate mechanisms of chemically induced cell injury and cell death and their implications for human health. Among;
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proliferation and cell death. This book aims to explain the molecular mechanisms that lie behind the multiplication and survival of eukaryotic cells;
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neurodegenerative models; death of neuronal and glial cells induced by photodynamic treatment; cell death during cerebellar development and the fundamental;
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Addressing a major field of interest for oncologists, cell biologists, and other biomedical researchers, Beyond Apoptosis provides an;
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Addressing a major field of interest for oncologists, cell biologists, and other biomedical researchers, Beyond Apoptosis provides an;
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allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates Discusses the role;
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, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human;
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discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development;
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migration, cell differentiation, cell death, axon guidance, and synaptogenesis. On a molecular level, there are several ways to categorize the;
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regulatory mechanisms that operate in stem cells Stem cells from a therapeutic perspective, including preparations of stem cells and their;
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This new volume of Current Topics in Developmental Biology covers Stem Cells in Development and Disease. The chapters provide a;
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state. The identification of a number of genes thought to play a role in the cell death, and development of both toxin and genetic models to;
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of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can;
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induce their development and realisation of survival or cell death scenario. Microtubular cytoskeleton is known as one of the principle players;
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substrate metabolism, energy production, and programmed versus sporadic cell death Offers insights on the development of strategies for targeted;
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in yeast, Mutual regulation of autophagy and necroptosis, Therapeutic inhibition of cell death by autophagy induction, and Necroptosis;
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of this process. This book brings together the latest international research on the complex subject of programmed cell death, and covers such;
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responsiveness to chemotherapy. This book reviews these recent advances and provides a foundational background and hints of new opportunities for basic;
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provides a thorough understanding of the mechanisms responsible for cellular aging, covering the recent research on programmed cell death and;
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blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for;
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