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volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics." Provides invaluable information on the exciting and fast;
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Histone deacetylase inhibitors (HDIs) are good anti-cancer targets. Histone acetyltransferases (HATs) and HDIs play opposite roles in the;
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) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest;
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The first chapter of Horizons in Cancer Research. Volume 72 discusses the Ewing's sarcoma family of tumors, including classic Ewing's;
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Volume 148 begins by summarizing recent findings in exosome research, highlighting the importance of exosomes as novel biomarkers and;
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Besides surgery, radiation therapy, endocrine therapy or chemotherapy, which were widely used in cancer patients for decades, the 21st;
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Cervical cancer is a malignancy of the cervix. World-wide, it is the second most common cancer of women. It may be present with vaginal;
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, representing nearly one third of all paediatric cancers. In this book, the authors present topical research in the study of acute lymphoblastic;
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of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic;
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aminoguanidine, a proven AGE inhibitor, was tested as an anti-diabetic drug in clinical trials showed critical side effects, which suggested a need for;
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diagnosis and prognosis of cancer because its expression strongly correlates with the potential tumour progression. Ninety percent of human cancers;
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, as well as mouse models for cancer. Coverage also includes how to refine drug leads for suitability in clinical testing, the special issues;
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-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways;
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in numerous cancers.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines;
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Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre;
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Michael D. Wendt Protein-Protein Interactions as Drug Targets Shaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev;
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properties Many new scientific results, such as the latest discoveries in cancer inhibitors, new inhibitors from structural modification;
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. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative;
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, Topical Calcineurin Inhibitors, Rituximab, TNF-alpha Inhibitors, Thalidomide, Zinc, Dapsone, Spironolactone as an antiandrogen in the treatment;
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Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy;
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Breast Cancer is second only to Lung Cancer as the leading Cancer cause of death in women. In 2010 207,000 women will be diagnosed with;
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/>* Bradykinin receptor (new approach to pain therapy) * Histone deacetylase (new drugs for cancer) * 5-HT2c receptor modulators (various CNS;
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investigating cancer therapeutics. Includes full synthetic schemes of all approved and in-trial third generation inhibitors
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This book focuses on histone mutations, especially those mutations closely related to cancer. Genetic mutations and epigenetic alterations;
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Protease inhibitors (PIs), which are widely distributed in plants and animals and have a variety of functions, interfere with cancer;
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of plants, over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines;
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