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Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins

This book examines Au (I, III) complexes that selectively attack and inhibit zinc finger proteins (ZnFs) for potential therapeutic use. The;

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Engineered Zinc Finger Proteins

creation, evaluation, and delivery of artificial transcription factors (ATFs), methods for the creation and evaluation of zinc finger nucleases;

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Synthesis of Heterometallic Zinc-Gold and Lanthanide-Transition Metal Carbonyl Complexes and Reactivity Study of Pentaphosphaferrocene Towards Low-Valent Main Group Species

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Reactions of Gold(iii) Complexes with Alkenes in Aqueous Solution

environment. A brief overview of gold chemistry (focusing mainly on the +3 oxidation state) and the reactions of gold(III) complexes with simple;

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Protein Targeting with Small Molecules

coverage of advances in chemistry and assesses their impact on developing new therapeutics, making it ideal for chemical biologists and medicinal;

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Integrated Methods in Protein Biochemistry: Part A

bioswitches with new functions, Interaction and cross-talk of prelamin A with integral membrane zinc metalloproteases, An experimental protocol to;

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Metal Ions in Biological Systems: Volume 14

covers anti-inflammatory activities of copper and gold complexes and considers the role of metal ions and chelating agents in anti-viral;

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A Closer Look at Kinase Inhibition

A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms;

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Mitochondrial Oxidative Phosphorylation

subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a;

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Iridium(III) in Optoelectronic and Photonics Applications

for use in optoelectronic applications. Iridium(III) in Optoelectronic and Photonics Applications represents the definitive account;

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Protein Reviews Purinergic Receptors

The Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein;

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Protein Reviews - Purinergic Receptors

The Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein;

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Bioconjugate Techniques

synthetic polymers. Armed with this information and the abundant protocols provided, readers will form unique complexes that can be used for;

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RNA Genetics: Volume I

, and the viral/cellular proteins involved. It presents models for both initiation and elongation of RNA chains by the poliovirus replicase.;

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Metallo-Drugs

group metal ions, among them Ru(IIIII), Au(IIII), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(IIIII), Cu(I/II;

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Zinc Fingers

. In this book, the authors present current research in the study of the structure, properties and applications of zinc fingers.;

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Polyhedral Boron Hybrides in Use

This book is designed to highlight the current status and perspectives of application of polyhedral boron compounds and their metal;

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Gold and its Complexes in Anticancer Chemotherapy

. The emergence of gold and its complexes as promising anticancer chemotherapeutic agents have the potential to substitute or replace the;

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Genome Editing

, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular;

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Zinc-Based Nanostructures for Environmental and Agricultural Applications

Zinc-Based Nanostructures for Environmental and Agricultural Applications shows how zinc nanostructures are being used in agriculture;

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Gene Targeting and Embryonic Stem Cells

Gene Targeting and Embryonic Stem Cells is a practical guide designed for the rapidly growing number of researchers who are moving into;

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Ligands

and 3), metal complexes with biological activity (chapter 4), and shows the possibilities for co-ordination chemistry in the planning of metal;

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Barriers and Channels Formed by Tight Junction Proteins I, Volume 1257

, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight;

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GPCRs

. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer's disease, Parkinson's disease, cancer;

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Protein-protein Recognition

time to try to make generalizations about how and why proteins form complexes with each other. The emphasis of the book is on heteromeric;

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GTPases Regulating Membrane Targeting and Fusion

and disassembly of protein complexes that include regulators (GEFs and GAPs), effectors (tethers/motors) and fusion components (SNAREs) that;

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Progress in Inorganic Chemistry, Volume 59

Iron and Manganese Complexes as Molecular Catalysts for Challenging Oxidative Transformations;

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