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inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing;
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, biochemical, and computational approaches to biological issues. In RNA and DNA Editing: Methods and Protocols, leading experts in the field introduce;
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The RNA editing enzyme hsADAR1 (human adenosine deaminase that acts on RNA 1) converts adenosines to inosines in double-stranded RNA and;
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RNA editing. A diverse array of editing events has been characterized, affecting gene expression in organisms from viruses and single cell;
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, while offering the reader some perspective on the significance of such modifications in fine-tuning the structure and functions of mature RNA;
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interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range;
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effects may contribute to the progression of disease. It is rare to find such a wide-ranging perspective on this topic in one volume and this;
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bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery;
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, depends on its release from a variety of cell types, as a result of adenosine triphosphate (ATP) enzymatic breakdown of both intra- and;
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T cell receptor sequences, A-to-G mismatches from A-to-I RNA editing, trans-splicing, gene fusion, circular RNAs, and the presence of non;
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, CRISPRing protozoan parasites to better understand the biology of diseases, CRISPR based genome editing of Caenorhabditis elegans, and a variety;
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methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider;
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sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA;
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receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their;
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several decades. The field has advanced from the use of limited tools to examine receptor signaling and function to the use of various molecular;
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and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function;
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focused on the regulation of RNA synthesis (transcription); however, there is a growing recognition of and appreciation for the importance of the;
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This book offers a unique and comprehensive overview of key RNA-based technologies, as well as their development and applications for the;
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look like on celluloid.Keyed for use with the DVD versions of twelve animated films and loaded with spot-on analysis, acting tips, and;
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Soybeans are greatly used in many foods, such as tofu, soy milk and yogurt, and it plays an important role as a functional food in the;
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ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and;
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the Society of Editors, and holds a prominent place on the shelves of writers, editors and students alike. Authors Elizabeth Flann, Beryl Hill;
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confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. RNA;
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RNA Methodologies: A Laboratory Guide for Isolation and Characterization, Sixth Edition provides the most up-to-date ribonucleic acid;
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described in detail. This book serves as a valuable resource to researchers in the field of crop improvement; graduate and postgraduate students;
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translation are as important as the control of transcription. In all aspects of post-transcriptional gene regulation a crucial role for RNA binding;
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